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Jonathan Seidman, PhD

Contact

Jonathan Seidman, PhD: seidman@gentics.med.harvard.edu Susanne Bartlett (admin asst): Bartlett@genetics.med.harvard.edu

Website

http://genetics.med.harvard.edu/%7Eseidman

Biography

Dr. Jonathan Seidman is the Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics at Harvard Medical School. He received his undergraduate degree from Harvard University ('72) and his Ph.D. degree form the University of Wisconsin-Madison. His postdoctoral studies were carried out in Dr. Philip Leder's laboratory at the National Institute of Child Health and Human Development. He has been a member of the Genetics Department, Harvard Medical School since 1981. Over the past ten years his research has been directed towards understanding the molecular basis of several inherited disorders including familial hypertrophic cardiomyopathy, Holt-Oram Syndrome, familial hypocalciuric hypercalcaemia and non-sensorineural deafness.

Dr. Seidman is a member of The Genetics Society of America and the American Society of Human Genetics as well as being inducted into the National Academy of Science. He has received several awards including the Gill Heart Institute Award for Outstanding Contributions to Cardiovascular Research (2000), the 12th Annual Bristol-Myers Squibb Award for Distinguished Achievement in Cardiovascular Research (2002) jointly with Christine Seidman, MD and the Grand Prix Lefoulon-Delalande Institut de France 2007 jointly with Christine Seidman, MD .

Publications

1. Seidman JG, Seidman CE. The Genetic Basis for Cardiomyopathy: From Mutation Identification to Mechanistic Paradigms. Cell (Review). 2001;104:557-567.
2. Schmitt JP, Kamisago M, Asahi M, Li GH, Ahmad F, Mende U, Kranias EG, MacLennan DH, Seidman JG, Seidman CE. Dilated cardiomyopathy and heart failure caused by a mutation in Phospholamban. Science. 2003;299:1410-1413.
3. Arad M, Moskowitz IP, Paterl VV, Ahmad F, Perez-Atayde AR, Sawyer DB, Walter M, Li G-H, Burgon PG, Maguire CT, Stapleton D, Schmitt JP, Guo XX, Pizard A, Kuperschmidt S, Roden DM, Berul CI, Seidman CE, Seidman JG. Transgenic mice over-expressing mutant PRKAG2 define the cause of Wolff-Parkinson-White Syndrome in glycogen storage cardiomyopathy. Circulation. 2003;107:2850-2856.
4. Arad M, Maron BJ, Gorham JM, Johnson WH, Saul JP, Perez-Atayde AR, Spirito P, Wright, GB, Kanter RJ, Seidman CE and Seidman JG. Glycogen storage diseases presenting as hypertrophic cardiomyopathy. New Engl. J Med. 2005;352(4):362-372.
5. Kim JB, Porreca GJ, Song L, Greenway S, Gorham JM, Church GM, Seidman CE, Seidman JG. Polony multiplex analysis of gene expression (PMAGE) of the adult mouse heart. Science. 2007; In Press

Last updated 10/19/2007.